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A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice
Published on: July 21, 2018
The elevated T-maze as a measure of two types of defensive reactions: a factor analysis
José Carlos Miranda Torrejais1, Camila Castilho Machado Rosa, Roseli Boerngen-Lacerda
1Laboratório de Fisiologia e Farmacologia do Sistema Nervoso Central, Departamento de Farmacologia, Universidade Federal do Paraná, Curitiba, Brazil.
Abstract:
Using factor analysis, we investigated whether the defensive reactions seen in the elevated T-maze measure different behaviours. Rats were submitted to the elevated T-maze followed by the open-field test. Avoidance 1 and 2 loaded on the same factor, while escape 2 and 3 loaded on a second factor. Baseline avoidance did not load together with locomotor activity in the open-field. These results indicate that the elevated T-maze generates two different defensive behaviours.
