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An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
Peritoneal carcinomatosis in urinary bladder cancer
Baris Turkbey1, Ceyla Basaran, Musturay Karcaaltincaba
1Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey. bturkbey@yahoo.com
Clinical Imaging
|May 27, 2008
Summary
Computed tomography (CT) identified peritoneal carcinomatosis in 7.6% of urinary bladder cancer patients. Detecting this spread via CT can significantly impact treatment decisions for better patient outcomes.
Area of Science:
- Radiology
- Oncology
- Urology
Background:
- Peritoneal carcinomatosis is a significant predictor of poor prognosis in cancer patients.
- Urinary bladder cancer can metastasize to the peritoneum, impacting treatment strategies.
- Accurate detection of peritoneal involvement is crucial for effective management.
Purpose of the Study:
- To describe the computed tomography (CT) findings associated with peritoneal carcinomatosis in patients diagnosed with urinary bladder cancer.
- To evaluate the prevalence and patterns of peritoneal spread in this patient cohort.
Main Methods:
- Retrospective review of CT scans from 105 patients with urinary bladder cancer.
- Analysis of imaging for peritoneal implants, ascites, solid organ metastases, and retroperitoneal lymphadenopathy.
- Correlation with surgical history and follow-up data.
Main Results:
- Peritoneal carcinomatosis was identified in 8 (7.6%) of the reviewed patients.
- Patterns of peritoneal involvement included diffuse disease (3 patients) and focal implants (5 patients).
- Associated findings included liver metastases (2 patients) and distant implants (pleural, adrenal).
Conclusions:
- CT is valuable in detecting peritoneal carcinomatosis in urinary bladder cancer.
- Preoperative identification of peritoneal involvement can guide treatment, potentially avoiding aggressive surgery.
- The presence of peritoneal carcinomatosis indicates a poor prognosis, necessitating careful management planning.
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