Related Experiment Video
Updated: Jul 5, 2026

03:19
Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
[Maternal vitamin D status in Martinique].
F M Mbou1, F Pagès-Lutz, M Garabédian
1Service de pédiatrie, centre hospitalier du Lamentin, 97232 Lamentin, Martinique. felicien.mbou@ch-lamentin.fr
Summary
Pregnant women in Martinique with adequate sun exposure do not routinely require vitamin D supplementation. Vitamin D levels were sufficient in most women, indicating no need for systematic supplementation.
Area of Science:
- Obstetrics and Gynecology
- Nutritional Science
- Endocrinology
Context:
- Martinique, a Caribbean region, offers year-round sunshine conducive to endogenous vitamin D production.
- Pregnancy necessitates careful consideration of vitamin D status due to its role in maternal and fetal health.
- Previous research often supports vitamin D supplementation during pregnancy, but regional variations in sun exposure warrant specific evaluation.
Purpose:
- To assess vitamin D status in pregnant women in Martinique.
- To evaluate the necessity of routine vitamin D supplementation for pregnant women in this tropical region.
- To determine if current supplementation practices align with observed vitamin D levels.
Summary:
- A prospective study evaluated 63 healthy pregnant women at term delivery in Martinique.
- Maternal serum 25-hydroxyvitamin D [25(OH)D] levels were measured, alongside calcium, phosphates, and alkaline phosphatase.
- Only 16% of women received vitamin D supplementation; mean 25(OH)D levels were 32.6 ng/ml, with no values below 13 ng/ml.
Impact:
- Findings suggest that systematic vitamin D supplementation may not be necessary for pregnant women in Martinique without specific risk factors.
- This research could inform public health guidelines regarding vitamin D supplementation in similar tropical, high-sunlight regions.
- Highlights the importance of considering geographical and environmental factors in nutritional recommendations for pregnant populations.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Role of Vitamins in Maintaining Bone Health
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Connective Tissue Cell Types
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Development of Immunocompetence
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...