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Cofactor dependent conformational switching of GTPases

Vasili Hauryliuk1, Sebastian Hansson, Måns Ehrenberg

  • 1Department of Cell and Molecular Biology, Molecular Biology Program, Uppsala University, Uppsala, Sweden.

Biophysical Journal
|May 27, 2008
PubMed
Summary

This study presents a generalized scheme for GTPase action, refining models of guanine nucleotide exchange. It incorporates cofactors for conformational switching, offering a more nuanced view of regulation for small GTPases.

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