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Morphogenesis

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.

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Updated: Jul 5, 2026

Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo

Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo

Published on: October 17, 2011

Linear morphoea follows Blaschko's lines.

L Weibel¹, J I Harper

¹Department of Paediatric Dermatology, Great Ormond Street Hospital for Children, London WC1N 3JH, UK. lisaweibel@yahoo.de

The British Journal of Dermatology

|May 28, 2008

Summary

This summary is machine-generated.

Linear morphoea, a form of localized scleroderma, follows Blaschko's lines in children. This suggests a developmental origin for this skin condition.

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Last Updated: Jul 5, 2026

Tracking Morphogenetic Tissue Deformations in the Early Chick Embryo

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Published on: October 17, 2011

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

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Published on: June 2, 2020

Area of Science:

Dermatology
Developmental Biology
Genetics

Background:

The cause of morphoea (localized scleroderma) is unknown.
Previous suggestions linked linear morphoea to Blaschko's lines, indicating potential embryological origins.
The precise distribution of linear morphoea has not been thoroughly assessed.

Purpose of the Study:

To determine common clinical presentations of linear morphoea in pediatric patients.
To investigate whether linear morphoea distribution aligns with Blaschko's lines.

Main Methods:

A retrospective review of 65 children diagnosed with linear morphoea.
Clinical photographs were used to map skin lesions onto standardized charts.
Lesion overlays were compared with established Blaschko's lines using Adobe Illustrator.

Main Results:

The 'en coup de sabre' subtype was observed in 53% of patients.
Linear morphoea on the trunk and limbs occurred in 41% of cases.
Lesions were unilateral in 85% of children, with no left or right side preference.
A strong correlation was found between lesion distribution and Blaschko's lines.

Conclusions:

The findings strongly suggest that linear morphoea follows Blaschko's lines.
A hypothesis proposes that susceptible cells exist in a mosaic pattern, triggered by external factors, leading to linear morphoea.