Related Experiment Video
Updated: Jul 5, 2026

14:56
An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
The development of the negative pain thoughts questionnaire
Ana-Maria Vranceanu1, Steve Safren, James Cowan
1Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
Summary
The Negative Pain Thoughts Questionnaire (NPTQ) effectively measures negative cognitions in orthopedic patients. High NPTQ scores predict greater pain disability, aiding in identifying at-risk individuals for targeted interventions.
Area of Science:
- Orthopedic Surgery
- Pain Management
- Psychology
Background:
- Cognitive processes significantly influence pain perception, disability, and treatment outcomes.
- Existing measures do not specifically assess negative cognitions related to medical treatment in orthopedic pain patients.
Purpose of the Study:
- To develop and conduct preliminary testing of the Negative Pain Thoughts Questionnaire (NPTQ).
Main Methods:
- The NPTQ, an 11-item questionnaire, was developed to assess pain and treatment cognitions.
- It was administered to two patient samples in a surgical orthopedic practice, with the second sample also completing depression and disability measures.
Main Results:
- The NPTQ demonstrated internal consistency and unidimensionality.
- NPTQ scores positively correlated with disability and depression, and significantly predicted disability even when controlling for depression.
Conclusions:
- The NPTQ is a brief, administrable tool for identifying orthopedic patients at risk of poor outcomes.
- It can facilitate referrals for cognitive behavioral therapy, potentially reducing unnecessary surgeries, healthcare costs, and chronic pain development.
Related Concept Videos
Negative and Cognitive Symptoms of Schizophrenia
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative and Positive Feedback
Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires maintaining an internal dynamic equilibrium:

