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Updated: Jun 15, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
[Ross procedure versus mechanical aortic valve replacement in young adults]
Zsolt Nagy1, Kevin G Watterson
1Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Kardiológiai Intézet, Szívsebészeti Központ, Debrecen. zsoltlnagy@hotmail.com
The pulmonary autograft (Ross procedure) offers young adults freedom from anticoagulation and better left ventricular (LV) remodeling compared to mechanical valves, though it
Area of Science:
- Cardiovascular Surgery
- Heart Valve Replacement
- Aortic Valve Surgery
Context:
- Young adults undergoing aortic valve replacement present unique challenges.
- Comparing surgical outcomes of pulmonary autograft (Ross procedure) versus mechanical prostheses is crucial for long-term patient well-being.
- Patient selection is key for optimizing results in aortic valve surgery.
Purpose:
- To compare the clinical and echocardiographic outcomes of the Ross procedure versus mechanical aortic valve replacement in young adults.
- To evaluate complications, mortality, and long-term functional status in both surgical groups.
- To assess the impact on left ventricular (LV) remodeling after aortic valve replacement.
Summary:
- Thirty-four young adults (mean age 26.2 years) underwent aortic valve replacement with either a Ross procedure (n=17) or a mechanical prosthesis (n=17).
- No early mortality was observed. Late deaths occurred only in the mechanical valve group (n=2).
- The Ross group experienced fewer complications (endocarditis, pulmonary embolism) and showed significantly smaller LV dimensions and wall thickness post-operatively.
Impact:
- The pulmonary autograft provides freedom from anticoagulation and promotes superior LV mass regression in young adults.
- The Ross procedure allows for an unrestricted lifestyle, making it a potentially superior option for select young patients.
- While advantageous, the Ross procedure is not universally suitable due to specific patient factors and potential complications.
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