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Updated: Jul 5, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Impact of palliative gastrectomy in patients with incurable advanced gastric cancer
Chikara Kunisaki1, Hirochika Makino, Ryo Takagawa
1Department of Surgery, Gastroenterological Center, Yokohama City University, Minami-ku, Yokohama, Japan. s0714@med.yokohama-cu.ac.jp
Background:
The efficacy of palliative gastrectomy for incurable advanced gastric cancer remains debatable.
Patients And Methods:
The study group comprised a series of 164 patients who had undergone palliative gastrectomy. Survival and prognostic factors were evaluated by univariate and multivariate analyses.
Results:
The median survival time was 9 months. Univariate analysis identified the following as factors that adversely affected survival: larger and deeper undifferentiated tumors; peritoneal, hematogenous, or remaining lymph-node metastasis; a large number of non-curative factors; less extensive lymph-node dissection; and an absence of chemotherapy. The Cox proportional regression hazard model recognized histological type, hematogenous metastasis, peritoneal metastasis and chemotherapy as independent factors. Moreover, the number of non-curative factors independently affected the disease-specific survival. In patients with a single non-curative factor, histological type and adjuvant chemotherapy were independent prognostic factors.
Conclusion:
A randomized controlled study should be conducted in advanced gastric cancer patients with a single non-curative factor to confirm the usefulness of palliative gastrectomy followed by chemotherapy shown here.
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