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Updated: Jul 5, 2026
09:24
Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
Published on: February 11, 2021
[Permeability of wall small intestinal for protein antigens in human and laboratory animals]
Voprosy Pitaniia
|May 29, 2008
Abstract:
There is a review of modern literature data (predominantly from 1985 to 2007 devoted to the problem of intestinal macromolecular permeability and uptake. The questions are studied on molecular mechanisms of intestinal barrier functions disturbance, quantitative estimation of macromolecular absorption in human and laboratory animals. The problem is discussed on intestinal barrier functions dietary correction possibilities.
Related Concept Videos
01:19Absorption of Nutrients
Absorption refers to taking dietary nutrients from the intestinal lumen for transportation throughout the body. After digestion in the small intestine, carbohydrates, proteins, and fats are broken down into simpler forms. These essential macronutrients and other vital substances, such as vitamins, minerals, and water, are then prepared for absorption into the bloodstream.
Enterocytes, which are specialized polar epithelial cells, line the mucosa of the small intestinal walls. These cells...
Enterocytes, which are specialized polar epithelial cells, line the mucosa of the small intestinal walls. These cells...
01:12Protein Absorption
Proteins in the gastrointestinal tract typically come from food, but they can also originate from disintegrated cells or secreted enzymes. In the stomach, the enzyme pepsin breaks down these proteins into polypeptides. The fragments then move into the duodenum as a semi-fluid mass called chyme. Pancreatic proteases, such as trypsin and chymotrypsin, and intestinal brush border enzymes like carboxypeptidases further dismantle the polypeptides into tripeptides, dipeptides, and free amino acids.