Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
Antibiotic Selection00:57

Antibiotic Selection

Overview
Antimicrobial Proteins01:23

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and acquisition...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tracking Extended-Spectrum β-Lactamase-Producing <i>Escherichia coli</i> Across Human Communities and Dairy Ecosystems: A One Health Investigation.

Antibiotics (Basel, Switzerland)·2026
Same author

A One Health comparative genomic assessment of antimicrobial-resistant <i>Escherichia coli</i> in dairy farms in western Canada.

Applied and environmental microbiology·2026
Same author

Assessing the associations between antimicrobial use and antimicrobial susceptibility testing results in Clostridium perfringens in Canadian broiler chickens, turkeys, and layer chickens from 2018 to 2023.

Anaerobe·2026
Same author

One Health study of mobile colistin resistance (<i>mcr</i>) in <i>Salmonella enterica</i> in Canada, 2017-2022.

Microbiology spectrum·2025
Same author

Investigating the occurrence of antimicrobial resistance in the environment in Canada: a scoping review.

Canadian journal of microbiology·2025
Same author

Molecular epidemiology and in silico prediction of ciprofloxacin resistance in <i>Salmonella enterica</i> in Canada, 2017-2022.

Canadian journal of microbiology·2025

Related Experiment Video

Updated: Jul 5, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Antimicrobial use in the Alberta sheep industry.

Brent P Avery1, Andrijana Rajić, Margaret McFall

  • 1Public Health Agency of Canada, Laboratory for Foodborne Zoonoses, Guelph, Ontario N1G 5B2. brent_avery@phac-aspc.gc.ca

Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Veterinaire
|May 29, 2008
PubMed
Summary

Antimicrobial use in Alberta sheep flocks is primarily through injections, with penicillins and tetracyclines being common. Future studies should collect more detailed data on non-injectable antimicrobial use.

More Related Videos

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

Related Experiment Videos

Last Updated: Jul 5, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

Area of Science:

  • Veterinary Medicine
  • Animal Health
  • Antimicrobial Stewardship

Background:

  • Limited data exists on antimicrobial usage patterns in sheep farming.
  • A scrapie surveillance program in Alberta (2001-2002) provided an opportunity to collect sheep health data, including antimicrobial use.

Purpose of the Study:

  • To describe the patterns of antimicrobial use within the Alberta sheep industry.
  • To identify the most common administration routes and antimicrobial classes used in sheep.

Main Methods:

  • A questionnaire-based survey was administered to 212 sheep flocks contributing cull ewes to the surveillance program.
  • Data collected focused on flock-level antimicrobial administration methods and drug-specific information for injectable antimicrobials.

Main Results:

  • Injectable administration was the most frequent method, followed by in-feed, oral, and in-water routes.
  • Penicillins and tetracyclines were the most common antimicrobial classes used via injection.
  • Mastitis and respiratory problems were the primary reasons for injectable antimicrobial use in adult sheep.

Conclusions:

  • Injectable antimicrobials are prevalent in Alberta sheep flocks, particularly for treating mastitis and respiratory issues in adults.
  • Further research is needed to gather detailed drug-specific data for non-injectable antimicrobial routes and to assess usage in feedlots and other Canadian provinces.