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Surface Active Agents01:27

Surface Active Agents

Surfactants, named for their behavior at interfaces, positively adsorb at the interfaces of two phases, reducing interfacial tension. Their versatility as emulsifiers, detergents, and foaming agents stems from this ability. Surfactants, often termed amphiphiles, share the property of amphipathy, with molecules having both hydrophilic and hydrophobic portions. The hydrophilic part is called the head, and the hydrophobic part, including an elongated alkyl substituent, forms the tail.Surfactants...
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Surface Tension of Fluid01:22

Surface Tension of Fluid

Surface tension is a fundamental property of fluids, occurring at the boundary between a liquid and a gas or between two immiscible liquids. This phenomenon arises from the cohesive forces between molecules at the fluid's surface, creating an effect similar to a stretched elastic membrane. Inside each fluid, molecules are equally attracted in all directions by neighboring molecules, but surface molecules experience a net inward force, resulting in surface tension.
Surface tension varies with...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

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Related Experiment Video

Updated: Jul 5, 2026

Extraction and Characterization of Surfactants from Atmospheric Aerosols
09:34

Extraction and Characterization of Surfactants from Atmospheric Aerosols

Published on: April 21, 2017

Surfactants and the skin.

P Dykes1

  • 1Cutest Systems Ltd, 174, Whitchurch Road, Heath, Cardiff, CF4 3NB, UK.

International Journal of Cosmetic Science
|May 29, 2008
PubMed
Summary

Cleansing the skin removes its natural barrier, leading to potential damage and irritant dermatitis. Analyzing released skin materials can help develop gentler cleansers and assess individual sensitivity.

Area of Science:

  • Dermatology
  • Cosmetic Science
  • Surface Chemistry

Background:

  • The skin surface acts as a barrier against the external environment.
  • Cleansing removes accumulated substances but also compromises the stratum corneum and its lipids.
  • Repeated exposure to surfactants can cause skin damage and irritant dermatitis.

Purpose of the Study:

  • To analyze materials released from the skin during cleansing.
  • To investigate changes in skin physical properties post-washing.
  • To explore methods for assessing skin irritancy and developing non-irritant cleansers.

Main Methods:

  • Standard scrub procedure to collect released skin materials (corneocytes, lipids, proteins).
  • Measurement of skin surface pH and transepidermal water loss (TEWL) after washing.

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Last Updated: Jul 5, 2026

Extraction and Characterization of Surfactants from Atmospheric Aerosols
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Extraction and Characterization of Surfactants from Atmospheric Aerosols

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Enhanced Oil Recovery using a Combination of Biosurfactants
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Enhanced Oil Recovery using a Combination of Biosurfactants

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Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces
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Microtensiometer for Confocal Microscopy Visualization of Dynamic Interfaces

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  • Patch testing to assess individual susceptibility to irritant dermatitis.
  • Main Results:

    • Cleansing with detergents and mechanical stimulation releases corneocytes and intercorneocyte lipids/proteins.
    • Washing alters skin surface pH and increases TEWL, indicating barrier disruption.
    • Individual variations in susceptibility to irritant dermatitis can be identified via patch testing.

    Conclusions:

    • Analysis of released skin components can guide the selection of surfactants.
    • Skin function measurements (TEWL, blood flow) offer objective indices of cleansing-induced damage.
    • Developing non-irritant cleansers may involve pre-selecting subjects based on sensitivity and using functional assays.