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Hemifacial spasm. Occurrence in multiple sclerosis.

F F Telischi1, L R Grobman, W A Sheremata

  • 1Department of Otolaryngology, University of Miami School of Medicine, FL 33136.

Archives of Otolaryngology--Head & Neck Surgery
|May 1, 1991
PubMed
Summary
This summary is machine-generated.

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This study reports a previously undescribed association between hemifacial spasm and multiple sclerosis in North America. Magnetic resonance imaging revealed multiple sclerosis plaques, suggesting hemifacial spasm can be a neurological manifestation of the disease.

Area of Science:

  • Neurology
  • Neuroimaging
  • Neuroimmunology

Background:

  • Hemifacial spasm (HFS) is a neuromuscular disorder characterized by involuntary contractions of facial muscles.
  • Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
  • The association between HFS and MS has not been previously documented in North American literature.

Observation:

  • Six patients presenting with hemifacial spasm were evaluated.
  • All patients underwent magnetic resonance imaging (MRI) of the brain.
  • MRI revealed lesions consistent with multiple sclerosis in all patients.

Findings:

  • Multiple sclerosis plaques were identified in the brain MRI scans.
  • In two patients, plaques were specifically located near the facial nucleus on the affected side.

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  • These findings suggest a potential link between MS and HFS.

    • Implications:

    • Hemifacial spasm may serve as an early or presenting symptom of multiple sclerosis.
    • Magnetic resonance imaging is a valuable tool for investigating the etiology of hemifacial spasm.
    • The study supports a central, specifically nuclear, origin for hemifacial spasm in the context of multiple sclerosis.