Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 4, 2026

Murine Echocardiography and Ultrasound Imaging
09:00

Murine Echocardiography and Ultrasound Imaging

Published on: August 8, 2010

A novel platform device for rodent echocardiography.

Ingo Kutschka1, Ahmad Y Sheikh, Ramachandra Sista

  • 1Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA. ingo.kutschka@t-online.de

ILAR Journal
|May 29, 2008
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early Alzheimer´s disease blood biomarkers are associated with a higher risk for postoperative long-term cognitive decline: Insights from the FINDERI study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Long-term outcomes of venous graft preservation in a rat autologous transplant model.

Scientific reports·2026
Same author

Stem-Cell-Derived Biologic Ventricular Assist Tissue in Heart Failure.

The New England journal of medicine·2026
Same author

Evaluation of fully automated ApoE4 proteotyping for <i>APOE</i> ε4 genotype estimation in the FINDERI cohort.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Sutureless Aortic, Mitral, and Tricuspid Valve Replacement.

JACC. Cardiovascular interventions·2026
Same author

Long-term outcomes of aortic grafts after 2-week storage in a rat model of orthotopic aortic transplantation.

Naunyn-Schmiedeberg's archives of pharmacology·2026

A novel imaging platform standardizes rodent echocardiography, reducing variability and improving image quality. This device enables consistent, high-quality cardiac assessments in small animal models, crucial for disease research.

Area of Science:

  • Cardiovascular Research
  • Medical Imaging Technology
  • Small Animal Models

Background:

  • Echocardiographic data acquisition in rodents often suffers from significant variability due to inconsistent techniques.
  • Standardization is crucial for reliable assessment of cardiac function and disease progression in preclinical research.

Purpose of the Study:

  • To develop and evaluate a dedicated imaging platform for standardizing rodent echocardiography.
  • To assess the platform's ability to improve image quality and reduce inter-operator variability.
  • To test the platform's utility in a rodent model of cardiac disease.

Main Methods:

  • A novel boom-mounted platform with a transparent membrane and integrated anesthesia port was constructed.
  • The platform allows probe positioning from beneath the animal for standard echocardiographic views.

More Related Videos

Transthoracic Echocardiography in Mice
08:09

Transthoracic Echocardiography in Mice

Published on: May 28, 2010

Related Experiment Videos

Last Updated: Jul 4, 2026

Murine Echocardiography and Ultrasound Imaging
09:00

Murine Echocardiography and Ultrasound Imaging

Published on: August 8, 2010

Transthoracic Echocardiography in Mice
08:09

Transthoracic Echocardiography in Mice

Published on: May 28, 2010

  • The device was tested on Sprague-Dawley rats and spontaneously hypertensive rats undergoing coronary artery ligation.

    • Main Results:

    • The platform facilitated optimal animal positioning for various echocardiographic measurements.
    • Minimal variability was observed between different operators and time points.
    • Serial echocardiography in hypertensive rats showed significant decreases in fractional shortening and ejection fraction post-ligation (p < 0.01).

    Conclusions:

    • The novel imaging platform enables consistent, high-quality echocardiographic data collection in rats.
    • This technology has the potential to improve standardization and throughput in small animal cardiac research.
    • Further development could lead to standardized high-throughput echocardiographic analysis in disease models.