Related Experiment Video
Updated: Jul 4, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Reproducibility and geometric accuracy of the Fixster system during hypofractionated stereotactic radiotherapy
Peter Lindvall1, Per Bergström, Per-Olov Löfroth
1Department of Neurosurgery, Umeå University Hospital, Umeå, Sweden. peter_lindvall_nkk@hotmail.com
Background:
Hypofractionated radiotherapy has been used for the treatment of AVMs and brain metastases. Hypofractionation necessitates the use of a relocatable stereotactic frame that has to be applied on several occasions. The stereotactic frame needs to have a high degree of reproducibility, and patient positioning is crucial to achieve a high accuracy of the treatment.
Methods:
In this study we have, by radiological means, evaluated the reproducibility of the isocenter in consecutive treatment sessions using the Fixster frame. Deviations in the X, Y and Z-axis were measured in 10 patients treated with hypofractionated radiotherapy.
Results:
The mean deviation in the X-axis was 0.4 mm (range -2.1 - 2.1, median 0.7 mm) and in the Y-axis -0.3 mm (range -1.4 - 0.7, median -0.2 mm). The mean deviation in the Z-axis was -0.6 (range -1.4 - 1.4, median 0.0 mm).
Conclusion:
There is a high degree of reproducibility of the isocenter during successive treatment sessions with HCSRT using the Fixster frame for stereotactic targeting. The high reducibility enables a safe treatment using hypofractionated stereotactic radiotherapy.

