Calling on a million minds for community annotation in WikiProteins

Barend Mons1, Michael Ashburner, Christine Chichester

  • 1Erasmus Medical Centre, Department of Medical Informatics, Rotterdam, the Netherlands. b.mons@erasmusmc.nl

Genome Biology
|May 30, 2008
PubMed

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Protein Networks

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Conservation of Protein Domains02:26

Conservation of Protein Domains

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Protein Complex Assembly02:41

Protein Complex Assembly

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Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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