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Published on: December 15, 2014
Dynamic contrast-enhanced MRI and MR diffusion imaging to distinguish between glandular and stromal prostatic tissues
Susan Moyher Noworolski1, Daniel B Vigneron, Albert P Chen
1Department of Radiology and Biomedical Imaging, The University of California, San Francisco, San Francisco, CA, USA. sue@radiology.ucsf.edu
Purpose:
To compare peak enhancement (PE), determined from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and the magnetic resonance (MR) directionally-averaged apparent diffusion coefficient (
Materials And Methods:
MRI, MR spectroscopic imaging, DCE MRI and MR diffusion were evaluated in 17 untreated subjects with suspected or proven prostate cancer. PE and
Results:
The glandular-ductal tissues had lower PE [125+/-6.4 (% baseline)] and higher
Conclusions:
The very different MR results in the glandular-ductal versus stromal-low ductal tissues suggest that these tissues have different underlying structure. These results support the hypothesis that Gd-DTPA does not enter healthy prostatic glands or ducts. This may explain the higher PE and lower
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