Interplay between anion-pi and hydrogen bonding interactions
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Updated: May 24, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
Published on: November 29, 2013
Daniel Escudero1, Antonio Frontera, David Quiñonero
1Departament de Química, Universitat de les Illes Balears, 07122 Palma de Mallorca, Spain.
Abstract:
The interplay between two important noncovalent interactions involving aromatic rings is studied by means of high level ab initio calculations. They demonstrate that synergistic effects are present in complexes where anion-pi and hydrogen bonding interactions coexist. These synergistic effects have been studied using the "atoms-in-molecules" theory and the Molecular Interaction Potential with polarization partition scheme. The present study examines how these two interactions mutually influence each other.
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