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Updated: Jul 4, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
07:00

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

Test systems for measuring ocular parameters and visual function in mice.

Frank Schaeffel1

  • 1Section of Neurobiology of the Eye, University Eye Hospital, Calwerstrasse 7/1, 72076 Tubingen, Germany. frank.schaeffel@unituebingen.de

Frontiers in Bioscience : a Journal and Virtual Library
|May 30, 2008
PubMed
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New techniques allow precise measurement of vision and eye characteristics in mice. These methods aid myopia research, genetic studies, and drug development in animal models.

Area of Science:

  • Ophthalmology
  • Animal Models
  • Vision Science

Background:

  • Accurate measurement of visual and ocular parameters is crucial for mouse research.
  • Existing methods may be insufficient for detailed phenotyping and myopia studies.

Purpose of the Study:

  • To introduce novel techniques for comprehensive eye assessment in mice.
  • To provide tools for myopia development research and genetic/pharmacological studies.

Main Methods:

  • Description of new techniques for measuring refractive state.
  • Methods for assessing pupil responses, corneal curvature, and ocular dimensions.
  • Techniques for evaluating spatial vision in mice.

Main Results:

  • The described techniques enable detailed ocular measurements in mice.

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Last Updated: Jul 4, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
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A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
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  • These methods are suitable for studying myopia development.
  • The techniques are valuable for phenotyping mouse mutants.

    • Conclusions:

    • The developed techniques offer significant advancements for vision research in mice.
    • These methods support diverse applications including genetic and pharmacological studies.