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SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
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A role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex dimerization during

Elena Fdez1, Thomas A Jowitt, Ming-Chuan Wang

  • 1Institute of Parasitology and Biomedicine López-Neyra, Consejo Superior de Investigaciones Cientificas, 18100 Granada, Spain.

Molecular Biology of the Cell
|May 30, 2008
PubMed
Summary

Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex dimers play a crucial role in neurotransmission. Mutations affecting SNARE complex dimerization impair regulated exocytosis and neurosecretion.

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