Related Experiment Video
Updated: Jul 4, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Functional recovery differs between ischaemic and haemorrhagic stroke patients
Vera P M Schepers1, Marjolijn Ketelaar, Anne J M Visser-Meily
1Center of Excellence for Rehabilitation Medicine Utrecht, Rehabilitation Center De Hoogstraat, Rembrandtkade 10, Utrecht, The Netherlands. V.Schepers@dehoogstraat.nl
Journal of Rehabilitation Medicine
|May 30, 2008
Summary
Patients with cerebral infarction recover activities of daily living independence faster than those with intracerebral haemorrhage in the first year post-stroke. This difference impacts rehabilitation management strategies.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Stroke Research
Background:
- Stroke is a leading cause of long-term disability.
- Activities of daily living (ADL) independence is a key outcome measure post-stroke.
- Cerebral infarction and intracerebral haemorrhage are distinct stroke types with potentially different recovery trajectories.
Purpose of the Study:
- To compare the development of ADL independence in the first year post-stroke.
- To investigate differences between patients with cerebral infarction and intracerebral haemorrhage.
Main Methods:
- Longitudinal study of first-ever stroke patients in inpatient rehabilitation.
- Measurements of ADL independence using the Barthel Index at multiple time points up to 52 weeks.
- Generalized Estimating Equations used to analyze the relationship between stroke type and ADL recovery over time.
Main Results:
- Included 229 cerebral infarction and 45 intracerebral haemorrhage patients.
- Cerebral infarction patients demonstrated significantly faster ADL recovery between 12 and 26 weeks.
- Intracerebral haemorrhage patients showed a more restricted recovery window, with significant gains only up to 10 weeks, compared to 26 weeks for cerebral infarction patients.
Conclusions:
- Significant differences exist in ADL recovery rates between cerebral infarction and intracerebral haemorrhage.
- Rehabilitation management should consider these distinct recovery patterns.
- Tailored interventions may optimize outcomes for different stroke types.
Related Concept Videos
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:29Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...