Related Experiment Video
Updated: Jul 4, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
High-content assays in oncology drug discovery: opportunities and challenges
Elizabeth H Mouchet1, Peter B Simpson
1AstraZeneca Cancer Bioscience, Alderley Park, Macclesfield, Cheshire, SK10 3JZ, UK. Elizabeth.Mouchet@AstraZeneca.com
Abstract:
High-content screening (HCS), a process that combines fluorescence microscopic imaging and automated image analysis, has had a significant impact on drug discovery since its introduction in the mid 1990s. The application of HCS within pharmaceutical drug discovery has become widespread, notably within oncology drug discovery. The trends, challenges and considerations for HCS that affect the successful and pragmatic implementation of this process in drug discovery will be outlined.
Related Concept Videos
Drug Discovery: Overview
Targeted Cancer Therapies
There are several types of targeted therapies against specific...

