Related Experiment Videos
Diagnostic and therapeutic approaches to bleeding from lower parts of the digestive system
S Antić1, I Dimitrijević, V Marković
1Institute for Digestive Diseases, Clinical Center of Serbia, Belgrade.
Insights
Diagnosing lower gastrointestinal bleeding (LGIB) remains challenging. Colonoscopies successfully identified the cause in 76% of patients, with diverticulosis, polyposis, and colorectal cancer being the most frequent culprits.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Diagnostic Imaging
Background:
- Lower gastrointestinal bleeding (LGIB) presents a common yet complex challenge in clinical practice.
- Accurate localization of the bleeding source is often difficult, complicating timely and effective treatment.
- Existing diagnostic and therapeutic strategies require continuous review and refinement.
Purpose of the Study:
- To evaluate the diagnostic yield of colonoscopy in patients with LGIB.
- To identify the primary causes of LGIB in the studied population.
- To propose an optimized algorithm for the diagnosis and management of LGIB.
Main Methods:
- A retrospective analysis of 424 colonoscopies performed for LGIB over a two-year period.
- Detailed review of patient data, diagnostic findings, and treatment outcomes.
- Comparison of findings with existing literature on LGIB.
Main Results:
- Colonoscopy established an exact diagnosis in 76% of patients (324/424).
- The most common causes of LGIB were colorectal cancer (46.14%), diverticulosis (37.11%), and polyposis (10.3%).
- Findings align with established ranges reported in similar international studies (74%-89%).
Conclusions:
- Colonoscopy is a valuable tool for diagnosing LGIB, achieving a high diagnostic rate.
- Colorectal cancer, diverticulosis, and polyposis are the leading causes of LGIB.
- A structured diagnostic and treatment algorithm is essential for managing LGIB effectively, particularly for complex or rare cases.
Abstract:
Bleeding from the gastrointestinal tract represents relatively common diagnostic and therapeutic challenge in clinical work of gastroenterologists and surgeons. Bleeding from the lower GI (LGIB) is mostly caused by pathologic conditions of the colon, although the source of bleeding cannot always be exactly localized, thus rendering optimal and prompt therapy difficult. During two year period, at IlI department of the First Surgical Clinic in Belgrade, we performed 424 colonoscopies for LGIB. According to our results the exact diagnosis was established in about 76% (324 patients) showing a great similarity with the results of other published studies (varying between 74% and 89%). The most common causes of bleeding were diverticulosis (37.11%), polyposis (10.3%) and colorectal cancer (46.14%). Besides that we have mentioned some specific facts involving the diagnosis and treatment of LGIB with an accent on some rare conditions, like angiodysplasia. Review of the diagnostic procedures and treatment modalities of the LGIB is useful for everyone who meets with this type of pathology in clinical practice. The diagnostic approach and the surgical treatment of these patients may represent a great problem, since the planning of the operative procedure can be very difficult and with uncertain result. Based on the literary data and our experience we have tried to set the algorithm of the diagnostics and treatment of the LGIB.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...