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Diagnostic and therapeutic approaches to bleeding from lower parts of the digestive system

S Antić1, I Dimitrijević, V Marković

  • 1Institute for Digestive Diseases, Clinical Center of Serbia, Belgrade.

Insights

Diagnosing lower gastrointestinal bleeding (LGIB) remains challenging. Colonoscopies successfully identified the cause in 76% of patients, with diverticulosis, polyposis, and colorectal cancer being the most frequent culprits.

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Diagnostic Imaging

Background:

  • Lower gastrointestinal bleeding (LGIB) presents a common yet complex challenge in clinical practice.
  • Accurate localization of the bleeding source is often difficult, complicating timely and effective treatment.
  • Existing diagnostic and therapeutic strategies require continuous review and refinement.

Purpose of the Study:

  • To evaluate the diagnostic yield of colonoscopy in patients with LGIB.
  • To identify the primary causes of LGIB in the studied population.
  • To propose an optimized algorithm for the diagnosis and management of LGIB.

Main Methods:

  • A retrospective analysis of 424 colonoscopies performed for LGIB over a two-year period.
  • Detailed review of patient data, diagnostic findings, and treatment outcomes.
  • Comparison of findings with existing literature on LGIB.

Main Results:

  • Colonoscopy established an exact diagnosis in 76% of patients (324/424).
  • The most common causes of LGIB were colorectal cancer (46.14%), diverticulosis (37.11%), and polyposis (10.3%).
  • Findings align with established ranges reported in similar international studies (74%-89%).

Conclusions:

  • Colonoscopy is a valuable tool for diagnosing LGIB, achieving a high diagnostic rate.
  • Colorectal cancer, diverticulosis, and polyposis are the leading causes of LGIB.
  • A structured diagnostic and treatment algorithm is essential for managing LGIB effectively, particularly for complex or rare cases.

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