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Related Concept Videos

Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...

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Related Experiment Video

Updated: Jul 4, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
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Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment

Published on: January 7, 2015

[Going through chemotherapy: an age-revealing process].

Sandro Anchisi1, Annick Anchisi

  • 1Oncologue médical, médecin chef service d'oncologie, Centre hospitalier du Centre du Valais, Hôpital de Sion, avenue Grand-Champsec 80, 1951 Sion, Valais, Suisse. sandro.anchisi@rsv-gnw.ch

Bulletin Du Cancer
|January 28, 2009
PubMed
Summary
This summary is machine-generated.

Elderly patients

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Modeling Chemotherapy Resistant Leukemia In Vitro
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Modeling Chemotherapy Resistant Leukemia In Vitro

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Last Updated: Jul 4, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
04:48

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment

Published on: January 7, 2015

Modeling Chemotherapy Resistant Leukemia In Vitro
08:41

Modeling Chemotherapy Resistant Leukemia In Vitro

Published on: February 9, 2016

Area of Science:

  • Geriatric Oncology
  • Psycho-oncology

Context:

  • Elderly patients undergoing chemotherapy face unique challenges.
  • Perceptions of life expectancy and treatment impact are key factors.

Purpose:

  • To explore the psychosocial and economic dimensions of chemotherapy in elderly individuals.
  • To highlight the importance of geriatric evaluation in cancer treatment.

Summary:

  • Chemotherapy can induce feelings of aging, social withdrawal, loneliness, and vulnerability in older adults.
  • Family support and addressing psychosocial/economic factors are crucial for successful treatment.
  • Geriatric evaluation should be a dynamic, ongoing process.

Impact:

  • Informs patient-centered care for elderly cancer patients.
  • Emphasizes holistic support beyond medical treatment.
  • Improves understanding of chemotherapy's lived experience in older populations.