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Rapid resensitization of purinergic receptor function in human platelets

S J Mundell1, J F Barton, M B Mayo-Martin

  • 1Department of Physiology and Pharmacology, School of Medical Sciences, University Walk, Bristol, UK.

Journal of Thrombosis and Haemostasis : JTH
|June 3, 2008
PubMed
Summary

Platelet responses to adenosine diphosphate (ADP) receptors P2Y(1) and P2Y(12) rapidly resensitize. Receptor internalization and recycling are crucial for this resensitization process in human platelets.

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