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Updated: Jul 4, 2026

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
Published on: May 30, 2025
Does the endoscopic finding of esophageal metastatic hepatocellular carcinoma progress from submucosal mass to
Chang Soo Choi1, Haak Cheoul Kim, Tae Hyeon Kim
1Department of Internal Medicine, Digestive Disease Research Institute, Wonkwang University College of Medicine, Iksan, Korea.
Background:
Esophageal metastasis of hepatocellular carcinoma (HCC) is extremely rare; it was not serially followed-up by endoscopy.
Objective:
Our purpose was to report the endoscopic findings according to the progression of esophageal metastatic HCC.
Design:
Case report.
Results:
In the review of the cases, submucosal tumor or polypoid mass were the most common endoscopic findings, and the locations of esophageal metastatic tumors are variable. The tumors had progressed from a submucosal mass to a polypoid mass in the current case.
Limitation:
Small number of cases.
Conclusions:
The endoscopic findings of esophageal metastasis of HCC may be changed from submucosal mass to polypoid mass.
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