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Related Concept Videos

Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Tooth Anatomy01:21

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Cranial Nerves: Types Part II01:22

Cranial Nerves: Types Part II

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...

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Updated: Jul 4, 2026

Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve
06:48

Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve

Published on: November 30, 2018

Peripheral nerve may regulate the jaw bone resorption after tooth extraction.

Li Tang1, Yue Chen, Yongyue Wang

  • 1Prosthetics Department, West China College of Stomatology, Sichuan Univesity, Chengdu, Si Chuan, China.

Medical Hypotheses
|June 3, 2008
PubMed
Summary
This summary is machine-generated.

Tooth extraction causes jaw bone loss, but nerve regeneration may prevent it. Promoting nerve growth could improve dental implant success and survival rates.

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Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve
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Area of Science:

  • Oral and Maxillofacial Surgery
  • Neuroscience
  • Bone Biology

Background:

  • Alveolar ridge resorption after tooth extraction complicates dental restorations.
  • Bone mass regulation involves complex hormonal, paracrine/autocrine, mechanical, and neuronal factors.
  • The nervous system significantly influences bone remodeling, with the hypothalamus integrating signals.

Purpose of the Study:

  • To investigate the role of alveolar bone innervation in regulating bone resorption post-extraction.
  • To explore the potential of nerve regeneration methods in preventing jaw bone loss.
  • To hypothesize the impact of innervation on dental implant healing and long-term survival.

Main Methods:

  • Review of existing literature on bone remodeling and neurobiology.
  • Analysis of observed axonal loss in edentulous bone post-extraction.
  • Formulation of a hypothesis based on neuro-osseous interactions.

Main Results:

  • Alveolar bone resorption after tooth extraction is a significant clinical challenge.
  • Loss of nerve axons is evident in edentulous alveolar bone.
  • Neuropeptides in bone marrow influence osteoblast and osteoclast activity.

Conclusions:

  • Innervation of alveolar bone likely plays a crucial role in regulating bone resorption.
  • Strategies promoting nerve regeneration may prevent jaw bone resorption after tooth loss.
  • Enhanced alveolar bone innervation could improve dental implant osseointegration and longevity.