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Updated: Jul 4, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Squamous cell carcinoma in a linear epidermal nevus.
Quratulain Masood1, Deepak Narayan
1Army Medical College, National University of Sciences and Technology, Pakistan.
Summary
A rare case of squamous cell carcinoma developed in a congenital epidermal nevus on a woman's thigh. This extremely uncommon cancer occurrence highlights the importance of monitoring such benign skin conditions.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Squamous cell carcinoma (SCC) is a common skin cancer.
- Congenital linear epidermal nevus is a rare birthmark.
Observation:
- An 81-year-old female presented with a 3-year history of a slowly enlarging mass on her left thigh.
- The mass was located on the site of a pre-existing congenital linear epidermal nevus.
Findings:
- Histological examination confirmed the mass as a well-differentiated squamous cell carcinoma.
- This represents an extremely rare instance of SCC arising within an epidermal nevus, with fewer than 10 reported cases.
Implications:
- This case underscores the potential for malignant transformation in congenital epidermal nevi.
- Highlights the need for vigilance and potential monitoring of these rare skin lesions.
- Contributes to the limited literature on SCC arising in epidermal nevi.
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