Related Experiment Video
Updated: Jul 4, 2026
09:11
Retinal Pathophysiological Evaluation in a Rat Model
Published on: May 6, 2022
[Proliferative diabetic retinopathy inauguring gestational diabetes]
1Institut Hédi-Raïs d'ophtalmologie, Tunis, Tunisie. nadiakhaldiophtalmo@yahoo.fr
Annales D'Endocrinologie
|June 3, 2008
Summary
Severe proliferative diabetic retinopathy can occur at gestational diabetes diagnosis. Early fundus exams in pregnant women are crucial for preventing blindness from diabetic eye disease.
Area of Science:
- Ophthalmology
- Endocrinology
- Reproductive Medicine
Background:
- Diabetic retinopathy is a microvascular complication of diabetes, typically developing years after diagnosis.
- Gestational diabetes mellitus (GDM) presents a unique challenge during pregnancy.
Observation:
- A case of a 24-year-old pregnant woman with GDM is presented.
- Severe proliferative diabetic retinopathy was diagnosed concurrently with GDM.
- Treatment with argon laser photocoagulation was initiated for retinal ischemia.
Findings:
- The patient experienced disease progression to vitreous hemorrhage in the right eye despite treatment.
- This case represents an exceptionally early presentation of proliferative diabetic retinopathy in pregnancy.
- No similar cases were identified in existing medical literature.
Implications:
- Routine fundus examinations are recommended at the initial diagnosis of GDM.
- Early detection and intervention can prevent vision loss in young women with GDM.
- This highlights the importance of comprehensive eye screening in pregnant individuals with diabetes.
More Related Videos
04:36An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice
Published on: January 12, 2024
10:07Studying Diabetes Through the Eyes of a Fish: Microdissection, Visualization, and Analysis of the Adult tg(fli:EGFP) Zebrafish Retinal Vasculature
Published on: December 26, 2017
Related Concept Videos
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
01:20Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
01:22Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
01:26Diabetes Mellitus: Introduction
Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...
01:25Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
01:22Complications of Diabetes Mellitus
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...