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Related Concept Videos

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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
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Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Heritable bovine fetal abnormalities.

B K Whitlock1, L Kaiser, H S Maxwell

  • 1Department of Anatomy, Physiology & Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA. whitlbk@vetmed.auburn.edu

Theriogenology
|June 3, 2008
PubMed
Summary
This summary is machine-generated.

Inherited congenital anomalies in cattle, though uncommon, are significant due to trait selection. Understanding their characteristics and genetic testing is crucial for veterinary practitioners.

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Area of Science:

  • Veterinary Genetics
  • Animal Science
  • Reproductive Biology

Background:

  • Congenital bovine fetal anomalies stem from heritable, toxic, nutritional, and infectious causes.
  • Inherited defects, while often uncommon, are present in all cattle breeds and can be propagated through selective breeding.
  • These anomalies can be lethal, impact animal structure and function, and pose economic challenges in affected herds.

Purpose of the Study:

  • To review the characteristics of heritable congenital bovine fetal anomalies.
  • To inform veterinary practitioners about the potential for inherited defects in cattle.
  • To discuss the modes of inheritance, affected breeding lines, and genetic testing availability.

Main Methods:

  • Literature review of scientific publications on congenital bovine fetal anomalies.
  • Analysis of morphological characteristics and inheritance patterns.
  • Examination of genetic testing options for bovine defects.

Main Results:

  • Heritable anomalies are a significant, though not always frequent, cause of congenital defects in cattle.
  • Selective breeding practices can inadvertently propagate these inherited defects.
  • Information on specific inherited anomalies, their genetic basis, and testing is available for veterinary practitioners.

Conclusions:

  • Veterinary practitioners must be aware of and prepared to investigate inherited bovine fetal anomalies.
  • Understanding the mode of inheritance and affected lines is key to managing these defects.
  • Genetic testing offers a valuable tool for identifying and potentially controlling heritable defects in cattle.