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Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
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Physiology of Respiration II: Neurogenic Control of Respiration01:22

Physiology of Respiration II: Neurogenic Control of Respiration

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Energy Balance01:19

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Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
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Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
08:58

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice

Published on: June 19, 2019

Brain circuits regulating energy homeostasis.

Alfonso Abizaid1, Tamas L Horvath

  • 1Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, USA. alfonso_abizaid@carleton.ca

Regulatory Peptides
|June 3, 2008
PubMed
Summary
This summary is machine-generated.

The brain

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Control of Eating Behavior Using a Novel Feedback System
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Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Related Experiment Videos

Last Updated: Jul 4, 2026

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
08:58

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice

Published on: June 19, 2019

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Area of Science:

  • Neuroscience
  • Metabolic regulation
  • Energy homeostasis

Background:

  • Rising obesity rates drive research into energy balance control.
  • Neuroscience tools advance understanding of brain's role in metabolism and feeding.
  • Hormonal signals like leptin, insulin, and ghrelin are key regulators.

Purpose of the Study:

  • To review central neural mechanisms controlling energy balance and feeding.
  • To explore how hormones and intracellular signals impact metabolic function.
  • To examine the brain's role in maintaining energy homeostasis.

Main Methods:

  • Review of current neuroscience literature.
  • Analysis of intracellular signaling pathways.
  • Examination of mitochondrial roles in neuronal metabolism.
  • Investigation of synaptic plasticity and circuit alterations.

Main Results:

  • Hormones (leptin, insulin, ghrelin) trigger complex intracellular signals in neurons.
  • These signals modulate cellular metabolism, particularly mitochondrial function.
  • Neuronal signals induce synaptic plasticity, altering neural circuits.
  • These changes influence cellular, physiological, and behavioral responses to maintain energy balance.

Conclusions:

  • The brain employs intricate mechanisms to regulate energy homeostasis.
  • Intracellular signaling and synaptic plasticity are crucial for metabolic control.
  • Understanding these pathways is vital for addressing the obesity pandemic.