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Published on: March 27, 2018

Gender influence on hospital mortality after coronary artery bypass surgery

Mohammad H Mandegar1, Mehrab Marzban, Amir H Lebaschi

  • 1Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Asian Cardiovascular & Thoracic Annals
|June 3, 2008
PubMed

Insights

Gender does not independently influence hospital mortality after coronary artery bypass grafting (CABG). Differences in outcomes between men and women are explained by varying risk factor profiles, not sex alone.

Area of Science:

  • Cardiovascular Surgery
  • Medical Statistics

Background:

  • Controversy exists regarding gender's impact on hospital mortality following coronary artery bypass grafting (CABG).
  • Understanding gender-specific risk factors is crucial for improving patient outcomes after CABG.

Purpose of the Study:

  • To investigate the independent influence of sex on hospital mortality after isolated on-pump CABG.
  • To analyze and compare risk factors between male and female patients undergoing CABG.

Main Methods:

  • Analysis of 1,258 patients undergoing isolated on-pump CABG, with 19 in-hospital deaths.
  • Logistic regression modeling to assess the independent impact of various risk factors, including sex, on mortality.

Main Results:

  • Women were older, had higher BMIs, and more comorbidities like hypertension and diabetes compared to men.
  • Men exhibited higher rates of smoking, lower ejection fractions, and more myocardial infarctions.
  • Factors prevalent in deceased patients included female sex, congestive heart failure, low ejection fraction, diabetes, prior percutaneous interventions, and chronic lung disease.

Conclusions:

  • Sex was not found to be an independent predictor of hospital mortality after CABG.
  • Observed differences in mortality between genders are attributable to variations in their pre-existing risk factor profiles.

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