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Related Experiment Video

Updated: Jul 4, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
08:41

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Published on: February 9, 2016

Treating leukemia in a resource poor setting.

J Menon1, L Mathews, K K Purushothaman

  • 1Department of Pediatrics, Government Medical College, Thrissur, Kerala, India. janakimenon@hotmail.com

Indian Pediatrics
|June 3, 2008
PubMed
Summary
This summary is machine-generated.

Childhood acute lymphatic leukemia (ALL) treatment in India faces challenges due to limited specialized care access. This study highlights survival rates and suggests twinning specialized centers with peripheral hospitals to improve outcomes for pediatric cancer patients.

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Area of Science:

  • Pediatric Oncology
  • Hematologic Malignancies
  • Public Health in Developing Nations

Background:

  • Acute lymphatic leukemia (ALL) is the most frequent childhood cancer in India.
  • Many pediatric cancer patients in India lack access to specialized healthcare facilities.
  • This study examines treatment experiences in a non-specialized government setting.

Purpose of the Study:

  • To describe the treatment outcomes of childhood acute lymphatic leukemia (ALL) in a resource-limited setting.
  • To analyze survival and event-free survival rates for pediatric ALL patients.
  • To propose strategies for improving access to care for children with ALL in India.

Main Methods:

  • Retrospective analysis of case records for 79 pediatric patients diagnosed with ALL.
  • Treatment was administered at a Government Medical College in Kerala over a 15-year period.
  • Evaluation of survival and event-free survival data for patients completing treatment.

Main Results:

  • Out of 73 patients who completed treatment, 23 (36%) survived.
  • Twenty patients achieved event-free survival exceeding 5 years post-remission.
  • Resource utilization within the described setting was documented.

Conclusions:

  • Achieving significant survival rates for childhood ALL is possible even in peripheral centers with dedicated efforts.
  • Twinning specialized cancer centers with peripheral hospitals can enhance care delivery and reach more children.
  • Improved healthcare infrastructure and collaborative models are crucial for pediatric cancer management in India.