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Testing the embryo, testing the fetus.

K Ehrich¹, B Farsides, C Williams

¹King's College London, School of Social Science and Public Policy, Centre for Biomedicine and Society.

Clinical Ethics

|June 3, 2008

Summary

This study explores ethical dilemmas in preimplantation genetic diagnosis (PGD) for genetic disorders. It examines staff views on embryo selection versus pregnancy termination, questioning gradualist moral status accounts.

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Area of Science:

Reproductive Medicine
Bioethics
Genetics

Background:

Preimplantation genetic diagnosis (PGD) involves ethical considerations regarding embryo selection and disposal.
Practitioners and scientists face complex social, ethical, and clinical dilemmas in PGD.
Comparing PGD with post-natal diagnosis (PND) raises distinct ethical questions.

Purpose of the Study:

To explore practitioners' and scientists' views on ethical dilemmas in PGD for serious genetic disorders.
To analyze staff experiences with embryo selection, transfer, and disposal.
To evaluate the adequacy of gradualist accounts of embryo/fetus moral status in PGD contexts.

Main Methods:

Ethnographic, multidisciplinary study.
Qualitative data collection on staff perceptions and experiences.
Analysis of ethical and clinical dilemmas in PGD.

Main Results:

Staff perceptions highlight the ethical complexities of embryo selection and disposal in PGD.
The study identifies potential advantages of PGD over termination following PND.
Gradualist accounts of moral status may not fully encompass all PGD-related ethical considerations.

Conclusions:

PGD presents unique ethical challenges distinct from those in PND.
The moral status of embryos requires nuanced consideration, potentially beyond developmental stage alone.
Further ethical frameworks are needed to address the complexities of PGD, including in-vitro versus in-utero considerations.