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Updated: Jul 4, 2026
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Chick ex ovo Culture and ex ovo CAM Assay: How it Really Works
Published on: November 30, 2009
The chick embryo chorioallantoic membrane in the study of tumor angiogenesis
1Department of Human Anatomy and Histology, University of Bari Medical School, Italy. ribatti@anatomia.uniba.it
Abstract:
The chick embryo chorioallantoic membrane (CAM) is commonly used as an experimental in vivo assay to study both angiogenesis and antiangiogenesis in response to tissues, cells or soluble factors. This article summarizes literature data about the use of the CAM in the study of tumor angiogenesis and particularly our experimental data concerning the study of angiogenesis in multiple myeloma and in neuroblastoma.
