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The Thyroid Gland

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

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Related Experiment Video

Updated: Jul 4, 2026

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach

Published on: September 15, 2023

LigaSure in total thyroidectomy.

Calogero Cipolla¹, Giuseppa Graceffa, Luigi Sandonato

¹Department of Oncology, University of Palermo, AOU Policlinico Paolo Giaccone, Palermo, Italy.

|June 3, 2008

Summary

This summary is machine-generated.

LigaSure vessel sealing is safe for thyroid surgery but does not reduce complications or operating time compared to traditional methods. Higher costs were noted, suggesting no significant advantage for this specific surgical application.

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Area of Science:

Surgical Technology
Endocrine Surgery

Background:

LigaSure is a bipolar diathermy system designed for vessel sealing with minimal thermal spread.
Its application has expanded to thyroid surgery to mitigate risks like laryngeal nerve palsy and hypocalcemia, and to potentially shorten operation duration.

Purpose of the Study:

To evaluate the efficacy and safety of the LigaSure diathermy system in total thyroidectomy.
To compare LigaSure with traditional hemostatic procedures regarding operating time and postoperative complications.

Main Methods:

A prospective study involving 105 patients undergoing total thyroidectomy.
53 patients were treated with LigaSure, while 52 received traditional hemostatic procedures.
Outcomes assessed included operating times and postoperative complications such as hemorrhage, hypocalcemia, and laryngeal nerve palsy.

Main Results:

No significant difference in mean operating time between the LigaSure group (104 +/- 12.7 min) and the traditional group (110 +/- 15.6 min).
Incidence of hemorrhage, definitive hypocalcemia, and definitive laryngeal nerve palsy was nil in both groups.
Transient hypocalcemia and laryngeal nerve palsy rates were similar between the LigaSure and traditional groups (7.54% vs 7.69% and 1.88% vs 1.92%, respectively).

Conclusions:

LigaSure serves as a safe and effective hemostasis method in thyroidectomy.
It did not demonstrate a significant reduction in operative complications or time compared to traditional techniques.
The study indicated higher operative costs associated with LigaSure without clear clinical benefits in this context.