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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Blood pressure prior to cardioversion predicts a conversion to sinus rhythm in patients with atrial fibrillation
J Kaluzay1, M Ferencik, K Mardiakova
14th Department of Internal Medicine, Faculty of Medicine and University Hospital, Comenius University, Bratislava, Slovakia. kaluzay@yahoo.com
Insights
Lower blood pressure (BP) before cardioversion is linked to higher success rates in atrial fibrillation (AF) patients. This finding identifies BP as a key predictor for successful AF cardioversion.
Area of Science:
- Cardiology
- Medical Research
Background:
- The impact of pre-cardioversion blood pressure (BP) on procedure success remains unexamined.
- Atrial fibrillation (AF) affects a significant patient population requiring cardioversion.
Purpose of the Study:
- To investigate the relationship between pre-cardioversion BP and the success rate of cardioversion in AF patients.
- To identify predictors of successful cardioversion.
Main Methods:
- Retrospective analysis of 92 cardioversions in 80 AF patients (mean age 62 years).
- Non-invasive BP measurements taken prior to cardioversion.
- Logistic regression analysis incorporating BP and various clinical factors.
Main Results:
- Cardioversion success rate was 60.9%.
- Successful cardioversions were associated with significantly lower mean, systolic, and diastolic BP.
- Identified optimal BP cut-off values for predicting success.
Conclusions:
- Lower pre-procedural BP is associated with successful cardioversion in AF patients.
- Both BP and antiarrhythmic therapy are significant predictors of cardioversion success.
Background:
The effect of BP measured prior to the cardioversion has not been studied.
Methods:
Eighty patients (mean age 62 +/- 11 yrs, 44 men) with atrial fibrillation (AF), who underwent 92 cardioversions, were included. Non-invasive BP was measured. We performed a retrospective review of clinical data. The variables included into logistic regression analysis were: BP, age, gender, arterial hypertension, coronary artery disease, heart failure, obesity, left atrial diameter, duration of AF, antiarrhythmic and antihypertensive therapy.
Results:
A success rate of cardioversion was 60.9%. BP was lower in the group of patients with a successful cardioversion (mean BP 97 +/- 15 vs 104 +/- 10 mmHg, p = 0.02; systolic BP 130 +/- 21 vs 140 +/- 18 mmHg, p=0.02; diastolic BP 81 +/- 14 vs 86 +/- 8 mmHg, p = 0.07). Mean, systolic and diastolic BP cut-off levels with the highest sum of sensitivity and specificity were 103, 138 and 75 mmHg, respectively.
Conclusions:
Subjects with a successful cardioversion had lower BP measured immediately prior to the procedure. BP and concurrent antiarrhythmic treatment were the only predictors of a successful cardioversion (Tab. 1, Ref. 29). Full Text (Free, PDF) www.bmj.sk.
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