Conformation and trapping rate of DNA at a convergent stagnation point
Jennifer Kreft1, Yeng-Long Chen, Hsueh-Chia Chang
1Institute of Physics, Academia Sinica, Taipei, Taiwan.
Abstract:
We use a lattice-Boltzmann based Brownian dynamics simulation to investigate the elongation of DNA at a convergent stagnation point trapped by a uniform attractive potential. The trapping rate of the DNA is not sensitive to the potential and, consistent with a mean field theory, scales as the Peclet number, Pe(1/3) . Surprisingly, we find that the coiled state is favored over the stretched state at high Pe. The final elongation is determined by conformation changes during transport to the stagnation point, rather than hydrodynamic stretching at that point.
More Related Videos
Related Concept Videos
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. Type I...
DNA as a Genetic Template
Single-Strand DNA Binding Proteins


