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Related Experiment Videos

Inclusions in the human thyroid.

G R Carpenter, J L Emery

    Journal of Anatomy
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Thyroid tissue in infants and children frequently contains thymus and parathyroid. Other common findings, like cartilage and ciliated epithelium, may also be normal variations in thyroid histology.

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    Area of Science:

    • Histopathology
    • Pediatric Endocrinology
    • Anatomy

    Background:

    • The normal histological composition of the pediatric thyroid gland is not fully established.
    • Incidental findings in thyroid tissue can lead to diagnostic uncertainty.

    Purpose of the Study:

    • To investigate the prevalence of various tissue types within the pediatric thyroid.
    • To determine if certain histological features are common enough to be considered normal variations.

    Main Methods:

    • Histopathological examination of 350 infant and child thyroid specimens.
    • Microscopic analysis to identify and quantify different tissue components.

    Main Results:

    • Presence of thymus and parathyroid tissue within the thyroid was common.

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  • Cartilage and ciliated epithelium were found in approximately 1% of specimens.
  • Compact masses of dark-staining cells, potentially with endocrine function, were frequently observed.

    • Conclusions:

    • The frequent occurrence of thymus and parathyroid tissue suggests they may be normal components of the pediatric thyroid.
    • Further research is needed to confirm the function of the observed dark-staining cells and their potential role in calcitonin production.