Related Experiment Video
Updated: Jul 4, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
Factors associated with remission from alcohol dependence in an American Indian community group
David A Gilder1, Philip Lau, Linda Corey
1Scripps Research Institute, 10550 North Torrey Pines Rd., SP30-1501, La Jolla, CA 92037, USA.
Objective:
This study identified factors associated with remission from DSM-III-R alcohol dependence in an American Indian community group.
Method:
Participants were assessed by using the Semi-Structured Assessment for the Genetics of Alcoholism.
Results:
Five hundred eighty participants were assessed for alcohol use and alcohol use symptoms; 254 participants were found to have alcohol dependence. The rate of remission in this group was 59%. Thirty-four percent of remitters and 39% of nonremitters had received treatment for alcohol problems. Remission from alcohol dependence was associated with being female, older, and married; an earlier age of onset of alcohol dependence; and self-reported depression symptoms from drinking. Absence of remission was associated with continuing to drink despite knowing one had medical problems from drinking and self-reported anxiety symptoms from drinking.
Conclusions:
Attention to factors associated with remission from alcohol dependence may be important in designing more effective treatment and prevention programs in this high-risk population.
More Related Videos
Related Concept Videos
Psychological and Sociocultural Causes of Schizophrenia
Drug Dependence
Factors Affecting Drug Response: Overview
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...
CNS Depressants: Alcohol and Nicotine
Alcohols from Carbonyl Compounds: Reduction
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...

