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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Conjunctival condylomata acuminata.

Joseph Iuorno¹, Alexander Truskinovsky, Gary Chung

¹Department of Ophthalmology, Virginia Commonwealth University, Richmond, VA, USA.

|June 4, 2008

Summary

Sexually transmitted human papillomavirus (HPV) can cause conjunctival squamous papillomas. This case suggests the term conjunctival condylomata acuminata for these HPV-related eye lesions.

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A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

Area of Science:

Ophthalmology
Dermatology
Infectious Diseases

Background:

Human papillomavirus (HPV) infections are common, typically affecting the anogenital region.
Conjunctival involvement with HPV is rare, presenting diagnostic challenges.

Observation:

A 31-year-old woman presented with bilateral, aggressive conjunctival papillomas.
She had a history of recurrent, biopsy-proven genital warts caused by HPV.

Findings:

Treatment with topical alpha-interferon 2b led to significant reduction in conjunctival lesions.
Histopathology revealed squamous papilloma with koilocytes, and molecular testing confirmed HPV type 11.
The conjunctival lesions showed similarities to anogenital warts.

Implications:

Proposes the term 'conjunctival condylomata acuminata' for sexually transmitted HPV-induced conjunctival lesions.
This term highlights the etiology and prompts screening for asymptomatic genital warts in patients and partners.
Emphasizes the importance of considering HPV in the differential diagnosis of conjunctival tumors.