Related Experiment Video
Updated: Jul 4, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Global cerebral hypoperfusion in a patient with transient global amnesia
Yumiko Yamane1, Kazunari Ishii, Kotaro Shimizu
1Institute for Aging Brain and Cognitive Disorders, Hyogo Brain and Heart Center, 520 Saisho-ko, Himeji, Hyogo, Japan.
Abstract:
We report a 64-year-old male patient with pure transient global amnesia (TGA) who exhibited global cerebral hypoperfusion during an amnesia attack. Initial single photon emission computed tomography (SPECT) performed 3 hours after the onset of the amnesic attack revealed diffuse hypoperfusion in the cerebrum, whereas a second SPECT study, 1 month later, revealed improvement of cerebral blood flow. This case suggests that SPECT study is useful in revealing the pathophysiological mechanism of TGA and that TGA attacks are associated with global cerebral blood flow change.
Related Concept Videos
Transient Ischemic Attack l: Introduction
Traumatic Brain Injury l: Introduction
Amnesia
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
Ischemic Stroke ll: Pathophysiology
Hepatic Encephalopathy
Cerebral Edema ll: Pathophysiology

