Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparing the sensory effects of menthol and synthetic coolants in e-liquids: A pilot investigation.

Experimental and clinical psychopharmacology·2026
Same author

Trajectories of Medical Prescription Opioid Use in Middle Adulthood and Substance Use Disorder Symptoms.

Psychiatric services (Washington, D.C.)·2026
Same author

'Sorry, I don't give away my medication': an examination of refusals todivert stimulant medication.

Addiction research & theory·2026
Same author

From cool to non-cool: California's 'non-menthol' cigarettes in 2025.

Tobacco prevention & cessation·2026
Same author

Water addition to e-liquids to reduce flavour aldehyde acetal formation: chemistry and user sensory experience and appeal.

Tobacco control·2026
Same author

Kratom Use and Associations With Mental Health in the United States.

Journal of addiction medicine·2026
Same journal

Navigating Uncertainty: Facilitating Parent-Child Conversations about Immigration Enforcement-Related Family Separation.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Trauma-Informed Principles on Informing Caregivers of Referrals to Child Protective Services.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Parental Support Increases Food Volume in Childhood Avoidant/Restrictive Food Intake Disorder, But What About Food Variety?

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Bringing Care Home: Intensive Community Services as a Viable Alternative to Adolescent Psychiatric Hospitalization.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Educational Attainment Polygenic Scores and School Performance in Adolescents With Psychiatric Disorders: A Population-Based Analysis of 86,122 Individuals From the iPSYCH2015 Case-Cohort.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Beyond Risk: The Case for Protective Factors in Adolescent Suicide.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
See all related articles

Related Experiment Video

Updated: Jul 4, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Characterizing adolescent prescription misusers: a population-based study.

Ty S Schepis1, Suchitra Krishnan-Sarin1

  • 1The authors are with the Department of Psychiatry, Yale University School of Medicine.

Journal of the American Academy of Child and Adolescent Psychiatry
|June 4, 2008
PubMed
Summary
This summary is machine-generated.

Adolescent prescription medication misuse is linked to poor academic performance, depression, risk-taking, and other substance use. Identifying these risk factors can aid early intervention for adolescents misusing prescription drugs.

Related Experiment Videos

Last Updated: Jul 4, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Area of Science:

  • Psychiatry
  • Public Health
  • Adolescent Medicine

Background:

  • Adolescent misuse of prescription drugs is a significant public health concern.
  • Understanding risk factors is crucial for targeted prevention and intervention strategies.

Purpose of the Study:

  • To identify risk factors associated with adolescent misuse of prescription opioids, stimulants, tranquilizers, and sedatives.
  • To analyze characteristics linked to abuse or dependence symptoms from prescription medication misuse in adolescents.

Main Methods:

  • Utilized data from the 2005 National Survey on Drug Use and Health, including 18,678 adolescents.
  • Employed regression analyses with population-based weights to determine predictors of misuse and substance use disorder symptoms.

Main Results:

  • 8.2% of adolescents misused prescription medication, and 3.0% showed symptoms of a related substance use disorder.
  • Key predictors of misuse included poor academic performance, major depression, risk-taking behavior, and use of alcohol, cigarettes, marijuana, cocaine, or inhalants.
  • Major depression, cocaine/inhalant use, and frequent prescription misuse episodes were associated with abuse/dependence symptoms.

Conclusions:

  • Identified significant risk factors for adolescent prescription medication misuse and related substance use disorders.
  • Findings can assist clinicians in identifying at-risk adolescents for early prevention and treatment of prescription misuse problems.