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Updated: Jul 4, 2026

Demystifying Venous Excess Ultrasound (VExUS): Image Acquisition and Interpretation
Published on: May 16, 2025
Multimodality imaging of the peripheral venous system.
1Unit of Ultrasound, Department of Medical Imaging, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9602, Haifa 31096, Israel.
Color Doppler duplex ultrasonography (CDDUS) is the top choice for diagnosing deep vein thrombosis (DVT). A combination of clinical assessment and D-dimer testing helps select patients, with phlebography used for unclear cases.
Area of Science:
- Vascular Medicine
- Diagnostic Imaging
- Radiology
Background:
- Deep vein thrombosis (DVT) is a significant clinical concern requiring accurate diagnostic methods.
- A variety of imaging techniques exist for DVT investigation, each with specific applications and limitations.
Purpose of the Study:
- To review the available image-based diagnostic tools for suspected deep vein thrombosis (DVT).
- To evaluate the efficacy and role of different venous imaging modalities in DVT diagnosis.
Main Methods:
- Review of author's experience and relevant publications on DVT imaging modalities.
- Inclusion of phlebography, color Doppler duplex ultrasonography (CDDUS), CT angiography/venography (CTA/CTV), MR venography (MRV), and radionuclide venography (RNV).
Main Results:
- Color Doppler duplex ultrasonography (CDDUS) is identified as the preferred diagnostic modality for DVT.
- A strategy integrating clinical scoring and D-dimer testing improves patient selection for imaging.
- Phlebography is reserved for cases with non-concordant non-invasive study results.
Conclusions:
- CDDUS is the recommended primary imaging tool for diagnosing DVT.
- Clinical assessment and D-dimer testing enhance diagnostic accuracy and patient stratification.
- Phlebography remains a valuable tool for resolving ambiguous non-invasive findings.
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