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Updated: Jul 4, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

Enhanced MDM2 Oncoprotein Expression in Soft Tissue Sarcoma: Several Possible Regulatory Mechanisms

R E Pollock1, A Lang, A K El-Naggar

  • 1Department of Surgical Oncology MD Anderson Cancer Center 1515 Holcombe Blvd, Box 106 University of Texas Houston TX 77030 USA.

Sarcoma
|January 1, 1997
PubMed
Summary

MDM2 oncoprotein over-production in soft tissue sarcoma is linked to DNA amplification and may involve post-transcriptional regulation, impacting cell cycle arrest and DNA repair. Therapeutic strategies targeting MDM2 over-production show promise.

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