Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Magnesium-Catalyzed Primary, Secondary, and Tertiary Amide Hydroboration.

Inorganic chemistry·2025
Same author

Medical Emergency Team calls within 24 hours of surgery and strategy for reduction.

Anaesthesia and intensive care·2018
Same author

Evaluating team-based inter-professional advanced life support training in intensive care-a prospective observational study.

Anaesthesia and intensive care·2017
Same author

Staples for intra-operative skin retraction in hand surgery.

Journal of hand and microsurgery·2014
Same author

Follow up of low grade sarcoma: the role of chest X-rays.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2014
Same author

Treatment of new-onset ulcerative colitis and ulcerative proctitis: a retrospective study.

Alimentary pharmacology & therapeutics·2012

Related Experiment Video

Updated: Jul 4, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Neurotized Free Muscle Flaps can Produce MRI Changes Mimicking Tumour Recurrence.

J K O'Neill1, J A Barrett, T Cobley

  • 1Departments of Radiology and Plastic and Reconstructive Surgery Royal Devon and Exeter Hospital Barrack Road Exeter EX2 5DW UK.

Sarcoma
|June 4, 2008
PubMed
Summary

Neurotized muscle flaps after surgery can mimic soft tissue sarcoma recurrence on MRI scans. High T2-weighted signal intensity in muscle requires clinical correlation to differentiate physiological changes from pathology.

More Related Videos

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Related Experiment Videos

Last Updated: Jul 4, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

Translational Orthotopic Models of Glioblastoma Multiforme
07:37

Translational Orthotopic Models of Glioblastoma Multiforme

Published on: February 17, 2023

Area of Science:

  • Radiology
  • Oncology
  • Surgical Reconstruction

Background:

  • Soft tissue sarcomas require Magnetic Resonance Imaging (MRI) for staging and follow-up.
  • Post-operative MRI findings of recurrent tumors include mass and high signal intensity on T2-weighted images.
  • High signal changes in skeletal muscle on T2-weighted images are not always specific indicators of pathology.

Purpose of the Study:

  • To describe a case where a neurotized muscle flap mimicked sarcoma recurrence on MRI.
  • To highlight the non-specific nature of high T2-weighted signal intensity in muscle post-reconstruction.
  • To emphasize the importance of clinical correlation in interpreting post-operative MRI findings.

Main Methods:

  • Case report detailing imaging findings in a patient who underwent reconstructive surgery with a free functioning muscle transfer and neurotization.
  • Review of Magnetic Resonance Imaging (MRI) T2-weighted sequences.
  • Comparison of imaging findings with clinical presentation.

Main Results:

  • Increased signal intensity was observed on T2-weighted MRI sequences in a neurotized muscle flap.
  • This finding raised concern for soft tissue sarcoma recurrence, despite no clinical evidence.
  • The high signal intensity was attributed to physiological changes in the neurotized muscle flap, not tumor recurrence.

Conclusions:

  • Neurotized muscle flaps can present with high T2-weighted signal intensity on MRI, mimicking sarcoma recurrence.
  • High signal intensity in muscle on T2-weighted images is not pathognomonic and requires careful clinical correlation.
  • Differentiating physiological changes from pathological conditions is crucial in post-operative oncologic imaging.