Related Experiment Video
Updated: Jul 4, 2026
07:06
Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
Published on: April 3, 2017
Multipotent menstrual blood stromal stem cells: isolation, characterization, and differentiation
Amit N Patel1, Eulsoon Park, Michael Kuzman
1Center for Cardiac Cell Therapy-Heart Lung Esophageal Surgical Institute, University of Pittsburgh/UPMC/McGowan Institute of Regenerative Medicine, Pittsburgh, PA 15213, USA. patelan@upmc.edu
Cell Transplantation
|June 5, 2008
Summary
Menstrual blood stem cells (MenSCs) are easily expandable and multipotent. These stem cells can differentiate into various cell types, showing promise for regenerative medicine research.
Area of Science:
- Stem cell biology
- Regenerative medicine
Background:
- Stromal stem cells possess self-renewal and multipotency.
- These properties enable multilineage differentiation.
Purpose of the Study:
- Characterize stromal stem cells from menstrual blood (MenSCs).
- Evaluate MenSC expansion and multipotency for regenerative medicine.
Main Methods:
- Isolate and expand MenSCs.
- Assess MenSC marker expression (Oct-4, SSEA-4, c-kit).
- Induce differentiation into chondrogenic, adipogenic, osteogenic, neurogenic, and cardiogenic lineages.
Main Results:
- MenSCs are easily expandable to clinical relevance.
- MenSCs express key multipotent markers.
- MenSCs successfully differentiate into multiple cell lineages.
Conclusions:
- MenSCs exhibit significant plasticity.
- MenSCs hold potential for regenerative medicine applications.
