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Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

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Updated: Jul 4, 2026

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
07:06

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

Published on: April 3, 2017

Human stem cell ethics: beyond the embryo.

Jeremy Sugarman1

  • 1Berman Institute of Bioethics, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. jsugarm1@jhmi.edu

Cell Stem Cell
|June 5, 2008
PubMed
Summary
This summary is machine-generated.

Human embryonic stem cell research involves ethical debates beyond embryo destruction. Key issues include cell sourcing, in vivo applications, intellectual property, and conflicts of interest in stem cell science.

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Derivation of Human Embryonic Stem Cells by Immunosurgery
11:56

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

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Last Updated: Jul 4, 2026

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
07:06

Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta

Published on: April 3, 2017

Derivation of Human Embryonic Stem Cells by Immunosurgery
11:56

Derivation of Human Embryonic Stem Cells by Immunosurgery

Published on: December 13, 2007

Area of Science:

  • Bioethics
  • Stem Cell Biology
  • Medical Research Ethics

Background:

  • Human embryonic stem cell (hESC) research is a prominent area of scientific advancement.
  • Ethical discussions frequently center on the destruction of human embryos for hESC derivation.
  • However, a broader spectrum of ethical considerations exists within stem cell research.

Purpose of the Study:

  • To identify and discuss ethical issues in stem cell research that are independent of embryo destruction.
  • To provide a comprehensive overview of the multifaceted ethical landscape of stem cell utilization.
  • To highlight areas requiring ethical deliberation beyond the initial procurement of cells.

Main Methods:

  • Literature review and ethical analysis.
  • Identification of distinct ethical domains within stem cell research.
  • Categorization of ethical challenges based on cell type, procurement, application, and commercialization.

Main Results:

  • Ethical concerns extend beyond embryo destruction to encompass cell procurement methods.
  • In vivo applications of stem cells present unique ethical considerations.
  • Intellectual property rights and conflicts of interest are significant ethical issues in stem cell commercialization and research.

Conclusions:

  • Ethical frameworks for stem cell research must address a wide array of issues.
  • Responsible innovation in stem cell science requires careful consideration of procurement, application, and commercialization ethics.
  • A holistic ethical approach is crucial for advancing stem cell research and therapies.