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Updated: Feb 10, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Percutaneous treatment of a single saphenous vein graft with two different protection devices
Francesco Bedogni1, Nuccia Morici, Nedy Brambilla
1Interventional Cardiology Department, Sant'Ambrogio Clinical Institute, Via Faravelli, 16-20149-Milano, Italy. fbedogni@tin.it
Insights
Catheter interventions in saphenous vein bypass grafts can cause embolization complications. This case study explores using both filter-based and proximal occlusion devices to protect against plaque debris during treatment.
Area of Science:
- Cardiovascular medicine
- Interventional cardiology
- Vascular surgery
Background:
- Catheter-based interventions are standard for saphenous vein aorto-coronary bypass grafts.
- These procedures risk distal embolization of atherosclerotic plaque, leading to complications.
- Existing protection devices, including occlusion and filter types, show similar efficacy.
Observation:
- This report details a case involving two distinct lesions within a single saphenous vein graft.
- A filter-based protection device was employed for the proximal lesion.
- A proximal occlusion balloon device was utilized for the distal lesion.
Findings:
- Both filter-based and proximal occlusion devices were used sequentially in the same saphenous vein graft.
- This approach addresses potential distal embolization during intervention.
- Comparable results were observed between the two device types in this scenario.
Implications:
- This dual-device strategy may offer a flexible approach to managing complex lesions in bypass grafts.
- Further research could validate the safety and effectiveness of combining different embolic protection devices.
- Optimizing embolic protection strategies is crucial for improving outcomes in bypass graft interventions.
Abstract:
Catheter-based intervention in saphenous vein aorto-coronary bypass is an established approach. Even if effective, this treatment can be associated with a high incidence of procedure-related complications, mainly because of distal embolization of atherosclerotic plaque. Both occlusion devices and filter-based protection devices have offered comparable results. In the case described below, two different lesions were treated in the same saphenous vein graft using a filter-based device for the proximal lesion and a proximal occlusion balloon for the distal one.
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