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Updated: Jul 4, 2026

07:13
Multimodal Cross-Device and Marker-Free Co-Registration of Preclinical Imaging Modalities
Published on: October 27, 2023
[MLC positioning checks and calibration with a portal imaging system]
Hans Schiefer1, Wolf W Seelentag, Jakob Roth
1Klinik für Radio-Onkologie, Kantonsspital St. Gallen, CH-9007 St. Gallen. johann.schiefer@kssg.ch
Zeitschrift Fur Medizinische Physik
|June 6, 2008
Summary
This study introduces an in-house program for checking Multi Leaf Collimator (MLC) leaf positions using Electronic Portal Imaging Device (EPID) images. The method accurately determines leaf positions relative to the radiation field, offering a cost-effective solution.
Area of Science:
- Medical Physics
- Radiation Oncology
- Image Analysis
Context:
- Accurate positioning of radiation therapy beams is crucial for treatment efficacy and patient safety.
- Current methods for verifying Multi Leaf Collimator (MLC) positioning may require specialized equipment or complex procedures.
- The need for efficient and accessible quality assurance tools in radiation oncology is paramount.
Purpose:
- To develop and validate a cost-effective method for precisely verifying the leaf positions of a Multi Leaf Collimator (MLC).
- To implement an in-house image analysis program utilizing Electronic Portal Imaging Device (EPID) images for MLC leaf position checks.
- To establish a reliable technique for transforming image coordinates to radiation field coordinates for accurate leaf tip determination.
Summary:
- The developed method uses EPID images with a marker plate containing known metal marker positions.
- Image analysis determines marker positions, enabling transformation to the radiation field coordinate system.
- This allows for exact determination of MLC leaf tip positions relative to the radiation field for arbitrary field shapes.
Impact:
- Provides a simple, cost-effective, and easily adaptable quality assurance tool for radiation therapy centers.
- Enhances the accuracy and reliability of radiation beam delivery by ensuring correct MLC positioning.
- Facilitates routine quality control of MLC performance, contributing to improved patient safety in radiotherapy.

