Related Experiment Video
Updated: Jul 4, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Contrast-enhanced magnetic resonance imaging guided decision making after primary percutaneous coronary intervention
Fabiola B Sozzi1, Laura Iacuzio, Filippo Civaia
1Cardiology, IRCCS Policlinico, Milan, Italy. fabiola_sozzi@yahoo.it
Insights
Contrast-enhanced magnetic resonance imaging (CE-MRI) precisely visualizes myocardial infarction, including the no-reflow zone. This technique aids in guiding therapeutic strategies for acute myocardial infarction, as demonstrated in a rare right ventricular infarction case.
Area of Science:
- Cardiology
- Medical Imaging
- Pathophysiology
Background:
- Coronary occlusion causes myocardial ischemia and necrosis, leading to microvascular obstruction (no-reflow phenomenon) in the infarct core.
- Contrast-enhanced magnetic resonance imaging (CE-MRI) identifies myocardial infarction as hyperenhanced regions with a hypoenhanced core.
Observation:
- CE-MRI provides detailed imaging of myocardial perfusion patterns and tissue damage.
- A rare case of right ventricular infarction was analyzed using CE-MRI.
Findings:
- CE-MRI accurately depicted the extent of myocardial damage and perfusion abnormalities in the infarct core.
- The no-reflow phenomenon was visualized, correlating with infarct core characteristics.
Implications:
- Assessment of the infarct core via CE-MRI is crucial for defining therapeutic strategies in acute myocardial infarction.
- This case highlights CE-MRI's role in directing interventional therapy and managing complex myocardial infarction presentations.
Abstract:
Coronary occlusion of large epicardial branches leads to profound ischemia at the infarct core, resulting in simultaneous necrosis of myocytes and endothelial cells. This process leads to microvascular obstruction in the infarct core, described as the no-reflow region in basic studies and documented in humans by contrast-enhanced magnetic resonance imaging and ultrasound. After coronary occlusion, contrast-enhanced magnetic resonance identifies myocardial infarction as a hyperenhanced region containing a hypoenhanced core. There is growing interest in incorporating its assessment into the evaluation of acute myocardial infarction because it is the key in defining specific therapeutic strategies and in directing the interventional therapy. We report a rare case of right ventricular infarction where contrast-enhanced magnetic resonance produced detailed images of myocardial perfusion pattern and tissue damage and directed the treatment after acute myocardial infarction.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Imaging Studies for Cardiovascular System IV: CMRI
